<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pimi</journal-id><journal-title-group><journal-title xml:lang="ru">Приборы и методы измерений</journal-title><trans-title-group xml:lang="en"><trans-title>Devices and Methods of Measurements</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-9506</issn><issn pub-type="epub">2414-0473</issn><publisher><publisher-name>BNTU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21122/2220-9506-2022-13-1-68-73</article-id><article-id custom-type="elpub" pub-id-type="custom">pimi-752</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Методы измерений, контроля, диагностики</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Methods of measurements, monitoring, diagnostics</subject></subj-group></article-categories><title-group><article-title>Оценка продолжительности сеанса лучевой терапии на этапе предлучевой подготовки</article-title><trans-title-group xml:lang="en"><trans-title>Assessing of a Radiation Therapy Sessionʼs Duration at the Stage of Pre-Radiation Preparation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петкевич</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Piatkevich</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Адрес для переписки: Петкевич М.Н. – РНПЦ онкологии и медицинской радиологии имени Н.Н. Александрова, агрогородок Лесной 223040, Минский район, Беларусь e-mail: maxpetkevichn@gmail.com</p></bio><bio xml:lang="en"><p>Address for correspondence: Piatkevich M.N. – N.N. Alexandrov National Cancer Centre of Belarus, Lesnoy 223040, Minsk District, Belarus e-mail: maxpetkevichn@gmail.com</p></bio><email xlink:type="simple">maxpetkevichn@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Титович</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Titovich</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>агрогородок Лесной 223040, Минский район</p></bio><bio xml:lang="en"><p>Lesnoy 223040, Minsk District</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>РНПЦ онкологии и медицинской радиологии имени Н.Н. Александрова</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>N.N. Alexandrov National Cancer Centre of Belarus</institution><country>Belarus</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>04</day><month>04</month><year>2022</year></pub-date><volume>13</volume><issue>1</issue><fpage>68</fpage><lpage>73</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Петкевич М.Н., Титович Е.В., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Петкевич М.Н., Титович Е.В.</copyright-holder><copyright-holder xml:lang="en">Piatkevich M.N., Titovich E.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://pimi.bntu.by/jour/article/view/752">https://pimi.bntu.by/jour/article/view/752</self-uri><abstract><p>Анализ плана лучевого лечения является неотъемлемой частью процесса предлучевой подготовки, в результате которого принимается решение о методике лечения пациента. Целью данной работы являлась разработка математической модели определения продолжительности сеанса лучевой терапии на этапе предлучевой подготовки.</p><p>Авторами предложены формула и алгоритм расчёта продолжительности сеанса облучения пациента на этапе дозиметрического планирования лучевого лечения. Разработано программное обеспечение расчёта продолжительности сеанса облучения, учитывающее значения всех параметров сеанса лучевой терапии: методику облучения, количество мониторных единиц, характеристики радиотерапевтического оборудования, количество радиационных полей, параметры полей облучения (углы поворота радиотерапевтического стола, коллиматора, штатива аппарата), наличие/ отсутствие дозомодулирующих устройств, мощность дозы, продолжительность верификации положения пациента. В программе предусмотрена установка стандартных параметров плана облучения для различных локализаций и методик путём выбора конкретного шаблона из выпадающего списка. В случае, если дозиметрический план не соответствует ни одному из шаблонов, в программе предусмотрен ввод параметров плана вручную.</p><p>Произведена оценка отклонений, рассчитываемых разработанной программой значений продолжительности сеанса лучевой терапии от истинных значений. Измерения проведены для 300 случаев: исследованы по 100 случаев для каждой методики облучения (IMRT, VMAT, 3D). Максимальное выявленное отклонение рассчитанного значения от истинного составило 2,3 % для методики облучения 3DCRT, для методик облучения IMRT и VMAT отклонение составило менее 1 %. Выявлено, что с увеличением количества процедур, напрямую связанных с действиями персонала, увеличивается и величина отклонения рассчитанного значения с измеренным.</p><p>Разработанное программное обеспечение позволяет оценивать временные параметры выбранных подходов дозиметрического планирования на рабочем месте медицинского физика. Оценка длительности сеанса лучевой терапии на этапе предлучевой подготовки способствует выбору оптимальной методики лучевого лечения с учётом индивидуальных параметров сеанса облучения в каждом конкретном клиническом случае.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>The treatment planning process includes a review of the radiation treatment plan which leads to a decision on the patientʼs treatment technique. The scope of this study was to create a mathematical model for calculating of a radiation therapy session duration during the pre-radiation planning stage.</p><p>For dosimetric planning of radiation treatment the authors provided a formula and an algorithm for determining of a patientʼs irradiation session duration. Radiation therapy session parameters such as radiation technique, number of monitor units, characteristics of radiotherapy equipment, number of radiation fields, radiation field parameters (angles of rotation of the radiotherapy coach, collimator, gantry), presence / absence of dose-modulating devices, dose rate, and duration of patient position verification procedures have all been taken into account during the development of software. The developed application explains how to define typical timing characteristics for various items as well as how to select a template from a built-in drop-down menu. If the dosimetric plan does not match for one of the templates, the program provides a space for defining of all parameters manually.</p><p>The anticipated deviations of the true indicators from the expected indicators of the duration of the radiation therapy session were assessed. A total of 300 cases have been completely measured, with 100 cases studied for each irradiation technique (IMRT, VMAT, 3D). The maximum detection confidence value for the 3DCRT irradiation technique is 2.3 %, while the deviation for the IMRT and VMAT irradiation techniques is less than 1 %. The magnitude and degree of the deviation of the measured value from the expected one for a variety of characteristics and features have been revealed to depend on the actions of the personnel.</p><p>The program developed allows medical physicists to analyze the timing parameters of the specified dosimetric planning methodologies directly on the treatment planning workstation. Evaluation of the duration of a radiation therapy session during the treatment planning stage, selection of various radiation treatment modalities, and consideration of the characteristics of the radiation session in each clinical case are available for analysis and further justified action.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>сеанс облучения</kwd><kwd>линейный ускоритель</kwd><kwd>лучевая терапия</kwd><kwd>временные характеристики</kwd></kwd-group><kwd-group xml:lang="en"><kwd>treatment session</kwd><kwd>linear accelerator</kwd><kwd>radiation therapy</kwd><kwd>timing</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Chernayev A.P., Lykova E.N., Popodko A.I. Medecynskoe oborudovanie v sovremennoi luchevoi terapii [Medical equipment in modern radiation therapy]. Moscow, OOP fizicheskogo fakulteta MGU, 2019, 101 p.</mixed-citation><mixed-citation xml:lang="en">Chernayev A.P., Lykova E.N., Popodko A.I. Medecynskoe oborudovanie v sovremennoi luchevoi terapii [Medical equipment in modern radiation therapy]. Moscow, OOP fizicheskogo fakulteta MGU, 2019, 101 p.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Selecting Megavoltage Treatment Technologies in External Beam Radiotherapy. International Atomic Energy Agency, ISSN 2074-7667, 2022, no. 17, 43 p.</mixed-citation><mixed-citation xml:lang="en">Selecting Megavoltage Treatment Technologies in External Beam Radiotherapy. International Atomic Energy Agency, ISSN 2074-7667, 2022, no. 17, 43 p.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Khan F.M. The physics of radiation therapy, 4th ed. Philadelphia, Lippincott Williams &amp; Wilkins, 2010, 531 p.</mixed-citation><mixed-citation xml:lang="en">Khan F.M. The physics of radiation therapy, 4th ed. Philadelphia, Lippincott Williams &amp; Wilkins, 2010, 531 p.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Trufanov G.E. Luchevaay terapia. Tom 2 [Radiation therapy, part 2]. Moscow, GEOTAR-Media, 2010, 192 p.</mixed-citation><mixed-citation xml:lang="en">Trufanov G.E. Luchevaay terapia. Tom 2 [Radiation therapy, part 2]. Moscow, GEOTAR-Media, 2010, 192 p.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Fotina I.E. Osnovy luchevoi terapii. Distantsionnaya radioterapiya [Fundamentals of Radiation Therapy. External beam therapy]. Tomsk, Izdatelstvo Tomskogo politekhnicheskogo universiteta, 2010, 104 p.</mixed-citation><mixed-citation xml:lang="en">Fotina I.E. Osnovy luchevoi terapii. Distantsionnaya radioterapiya [Fundamentals of Radiation Therapy. External beam therapy]. Tomsk, Izdatelstvo Tomskogo politekhnicheskogo universiteta, 2010, 104 p.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Tepper Joel E., Foote Robert L., Michalski Jeff M. [Clinical radiation oncology. Fifth edition]. Elsevier Philadelphia, PA, 2021, 1586 p.</mixed-citation><mixed-citation xml:lang="en">Tepper Joel E., Foote Robert L., Michalski Jeff M. [Clinical radiation oncology. Fifth edition]. Elsevier Philadelphia, PA, 2021, 1586 p.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Ovchinikov V.A., Uglyanitsa K.N., Volkov V.N. Sovremennye metody luchevogo lecheniya onkologicheskikh bolnykh [Modern radiation treatment methods for cancer patients]. Zhurnal GrSMU [Journal of Grodno State Medical University], 2010, no. 1, pp. 93–97 (in Russian).</mixed-citation><mixed-citation xml:lang="en">Ovchinikov V.A., Uglyanitsa K.N., Volkov V.N. Sovremennye metody luchevogo lecheniya onkologicheskikh bolnykh [Modern radiation treatment methods for cancer patients]. Zhurnal GrSMU [Journal of Grodno State Medical University], 2010, no. 1, pp. 93–97 (in Russian).</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Xia Ping, Godley Andrew (eds.) Strategies for radiation therapy treatment planning. Demos Medical Publishing, 2019, 319 p.</mixed-citation><mixed-citation xml:lang="en">Xia Ping, Godley Andrew (eds.) Strategies for radiation therapy treatment planning. Demos Medical Publishing, 2019, 319 p.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Khan F.M., Gibbons J.P. Khan’s the physics of radiation therapy, 5th ed. Philadelphia, Wolters Kluwer, 2014, 584 p.</mixed-citation><mixed-citation xml:lang="en">Khan F.M., Gibbons J.P. Khan’s the physics of radiation therapy, 5th ed. Philadelphia, Wolters Kluwer, 2014, 584 p.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Lykova E.N. Uzarova K.A. Vvedenie v planirovanie luchevoi terapii puchkami tormoznykh fotonov [Introduction to Beam Radiation Therapy Planning bremsstrahlung photons]. Moscow, OOP fizicheskogo fakulteta MGU, 2019, 108 p.</mixed-citation><mixed-citation xml:lang="en">Lykova E.N. Uzarova K.A. Vvedenie v planirovanie luchevoi terapii puchkami tormoznykh fotonov [Introduction to Beam Radiation Therapy Planning bremsstrahlung photons]. Moscow, OOP fizicheskogo fakulteta MGU, 2019, 108 p.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Titovich E.V., Patsiapalau P.A., Piatkevich M.N., Kiselev M.G. [The algorithm for determining timing of radiotherapy session components for different methods of oncology patients irradiation at the stage of radiotherapy planning]. Pribory i metody izmerenii [Devices and Methods of Measurements], 2017, vol. 8, no. 1, рр. 73–80 (in Russian). DOI: 10.21122/2220-9506-2017-8-1-73-80</mixed-citation><mixed-citation xml:lang="en">Titovich E.V., Patsiapalau P.A., Piatkevich M.N., Kiselev M.G. [The algorithm for determining timing of radiotherapy session components for different methods of oncology patients irradiation at the stage of radiotherapy planning]. Pribory i metody izmerenii [Devices and Methods of Measurements], 2017, vol. 8, no. 1, рр. 73–80 (in Russian). DOI: 10.21122/2220-9506-2017-8-1-73-80</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Titovich E.V, Piatkevich M.N., Makarava N.I. [Methodology of defining of the radiation therapy components for various methods of patients’ treatingusing medical linear accelerators and gamma-therapeutic devices]. Pribory i metody izmerenii [Devices and Methods of Measurements], 2020, vol. 11, no. 4, рр. 289–287. DOI: 10.21122/2220-9506-2020-11-4-289-287</mixed-citation><mixed-citation xml:lang="en">Titovich E.V, Piatkevich M.N., Makarava N.I. [Methodology of defining of the radiation therapy components for various methods of patients’ treatingusing medical linear accelerators and gamma-therapeutic devices]. Pribory i metody izmerenii [Devices and Methods of Measurements], 2020, vol. 11, no. 4, рр. 289–287. DOI: 10.21122/2220-9506-2020-11-4-289-287</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
