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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">pimi</journal-id><journal-title-group><journal-title xml:lang="ru">Приборы и методы измерений</journal-title><trans-title-group xml:lang="en"><trans-title>Devices and Methods of Measurements</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2220-9506</issn><issn pub-type="epub">2414-0473</issn><publisher><publisher-name>BNTU</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21122/2220-9506-2026-17-1-60-66</article-id><article-id custom-type="elpub" pub-id-type="custom">pimi-1032</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Методы измерений, контроля, диагностики</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Methods of measurements, monitoring, diagnostics</subject></subj-group></article-categories><title-group><article-title>Оценка влияния нерегулярности границы раздела болюс–фантом на неопределённость доставки дозы фотонного пучка</article-title><trans-title-group xml:lang="en"><trans-title>Measurement and Computational Approach for Evaluating the Effect of Physical Heterogeneity at the Bolus-Phantom Interface on Photon Beam Dosimetric Parameters</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чиркова</surname><given-names>И. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Chirkova</surname><given-names>I. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Адрес для переписки:РНПЦ онкологии и медицинской радиологии имени Н.Н. Александрова,агр. Лесной 223040, Минский район, Беларусь irinagutkovskaya@gmail.com</p></bio><bio xml:lang="en"><p>Address for correspondence:N.N. Alexandrov National Cancer Center of Belarus,Lesnoy 223040, Minsk District, Belarus irinagutkovskaya@gmail.com</p></bio><email xlink:type="simple">irinagutkovskaya@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тумилович</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tumilovich</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ул. П. Бровки, 6,г. Минск 220013</p></bio><bio xml:lang="en"><p>ул. П. Бровки, 6, г. Минск 220013</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петкевич</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Piatkevich</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>агр. Лесной 223040, Минский район</p></bio><bio xml:lang="en"><p>Lesnoy 223040, Minsk District</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>РНПЦ онкологии и медицинской радиологии имени Н.Н. Александрова,  &#13;
Белорусский государственный университет информатики и радиоэлектроники</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>N.N. Alexandrov National Cancer Center of Belarus,&#13;
Belarusian State University of Informatics and Radioelectronics</institution><country>Belarus</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Белорусский государственный университет информатики и радиоэлектроники</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>Belarusian State University of Informatics and Radioelectronics</institution><country>Belarus</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>РНПЦ онкологии и медицинской радиологии имени Н.Н. Александрова</institution><country>Беларусь</country></aff><aff xml:lang="en"><institution>N.N. Alexandrov National Cancer Center of Belarus</institution><country>Belarus</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>01</day><month>04</month><year>2026</year></pub-date><volume>17</volume><issue>1</issue><fpage>60</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Чиркова И.Н., Тумилович М.В., Петкевич М.Н., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Чиркова И.Н., Тумилович М.В., Петкевич М.Н.</copyright-holder><copyright-holder xml:lang="en">Chirkova I.N., Tumilovich M.V., Piatkevich M.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://pimi.bntu.by/jour/article/view/1032">https://pimi.bntu.by/jour/article/view/1032</self-uri><abstract><p>Обеспечение воспроизводимой доставки дозы к поверхностным и приповерхностным структурам при лучевой терапии является важной задачей клинической дозиметрии. Существенным источником неопределённости является нарушение контакта болюса с поверхностью тела, сопровождающееся формированием воздушных зазоров. Целью работы являлась оценка влияния нерегулярности границы «болюс–фантом» на дозовое распределение. Разработана методика, сочетающая плёночную дозиметрию Gafchromic EBT3, измерения ионизационной камерой и расчёты в системе Eclipse. Показано, что зазор 0–5 мм увеличивает поверхностную дозу до + 15 %, тогда как зазоры более 5 мм приводят к снижению до – 23 %; болюс толщиной 10 мм обеспечивает более стабильное дозовое покрытие, чем 5-миллиметровый болюс. Полученные результаты подчёркивают необходимость контроля контакта «болюс–поверхность тела» в процедурах планирования и контроля качества лучевой терапии.</p></abstract><trans-abstract xml:lang="en"><p>Modern radiation therapy requires reproducible dose delivery to superficial and near surface structures. An important source of uncertainty is the loss of contact between the bolus and the patient’s skin, leading to air gaps at the bolus–skin interface. The aim of this study was to assess the impact of bolus–phantom interface irregularities on dose distribution. A dedicated methodology was developed, combining Gafchromic EBT3 film dosimetry, ionization chamber measurements, and dose calculations in the Eclipse treatment planning system. Air gaps of 0–5 mm were found to increase the surface dose by up to + 15 %, whereas gaps larger than 5 mm reduced it by up to –23 %; a 10 mm bolus provided more stable dose coverage than a 5 mm bolus. These findings emphasize the need to control bolus–skin contact in treatment planning and quality assurance procedures in radiation therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лучевая терапия</kwd><kwd>болюс</kwd><kwd>радиохромная плёнка</kwd><kwd>фантом</kwd><kwd>неопределённость доставки дозы</kwd></kwd-group><kwd-group xml:lang="en"><kwd>radiation therapy</kwd><kwd>bolus</kwd><kwd>radiochromic film</kwd><kwd>phantom</kwd><kwd>dose delivery uncertainty</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Чиркова, И.Н. Анализ дозиметрических параметров модели распределения дозы ионизирующего излучения при моделировании облучения поверхности грудной клетки / И.Н. Чиркова, М.Н. Петкевич, М.В. Тумилович // Медэлектроника-2024: сборник научных статей XVI Международной научнотехнической конференции, Минск, 5-6 декабря 2024 г.: БГУИР/ М.В. Давыдов, И.И. Ревинская, В.В. Гоман. – Минск, 2024. – С. 260–265.</mixed-citation><mixed-citation xml:lang="en">Chirkova IN. Dependence of dose distribution of ionizing radiation on the selected method for calculating the irradiation plan. Medelectronics-2024, Collection of Abstracts of Reports of the 14th Shientific and Technical Conference, Minsk, 5–6 Dec. Minsk, Belarussian State University of Informatics and Radioelectronics. 2024;260265 рр. (In Russ.). P. 179-184.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ратнер, Т.Г. Клиническая дозиметрия. Физикотехнические основы / Т.Г. Ратнер, И.М. Лебеденко. – Изд. 2-е.–М.: НИЯУ МИФИ, 2022. – С. 47–49.</mixed-citation><mixed-citation xml:lang="en">Ratner TG, Lebedenko IM. (2022) Clinical dosimetry. Physical and technical foundations. 2022;47-49.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Khan, F.M. The physics of radiation therapy / F.M. Khan, J.P. Gibbons. – 5th ed. – Philadelphia: Lippincott Williams &amp; Wilkins, 2014. – P. 133–149.</mixed-citation><mixed-citation xml:lang="en">Khan FM, Gibbons JP. The physics of radiation therapy. 5th ed. Philadelphia: Lippincott Williams &amp; Wilkins. 2014;133-149.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Podgorsak, E.B. Radiation oncology physics: a handbook for teachers and students / E.B. Podgorsak. – Vienna : International Atomic Energy Agency, 2005. – P. 169–188.</mixed-citation><mixed-citation xml:lang="en">Podgorsak EB. Radiation oncology physics: a handbook for teachers and students. Vienna: International Atomic Energy Agency. 2005;169-188.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Van der Merwe, D.G. Surface doses for different radiation beams and delivery techniques / D.G. Van der Merwe, J. Van Dyk, B. Healy // Journal of Applied Clinical Medical Physics. – 2017. – Vol. 18, № 5. – P. 239–247. DOI: 10.1002/acm2.12145</mixed-citation><mixed-citation xml:lang="en">Van der Merwe DG, J. Van Dyk, B. Healy. Surface doses for different radiation beams and delivery techniques. Journal of Applied Clinical Medical Physics. 2017;18(5):239-247. DOI: 10.1002/acm2.12145</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Tang, C. Quantify the Effect of Air Gap Errors on Skin Dose for Breast Cancer Radiotherapy / C. Tang, J. Yuan, H. Guo [et al.] // Technology in Cancer Research &amp; Treatment. – 2024. – Vol. 23. – P. 1. DOI: 10.1177/15330338241258566</mixed-citation><mixed-citation xml:lang="en">Tang C. [et al.]. Quantify the Effect of Air Gap Errors on Skin Dose for Breast Cancer Radiotherapy. Technology in Cancer Research &amp; Treatment. 2024;23:1p. DOI: 10.1177/15330338241258566</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Bakai, A. Sensitivity of IMRT and VMAT to setup errors in the treatment of prostate cancer: a quantitative analysis / A. Bakai, F. Nüsslin // Medical Physics. – 2009. – Vol. 36, № 6. – P. 2310–2318. DOI: 10.1118/1.3134242</mixed-citation><mixed-citation xml:lang="en">Bakai A, Nüsslin F. Sensitivity of IMRT and VMAT to setup errors in the treatment of prostate cancer: a quantitative analysis. Medical Physics. 2009;36(6):23102318. DOI: 10.1118/1.3134242</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Almond, P.R. AAPM's TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams / P.R. Almond, P.J. Biggs, B.M. Coursey [et al.] // Medical Physics. – 1999. – Vol. 26, № 9. – P. 1847–1870. DOI: 10.1118/1.598691</mixed-citation><mixed-citation xml:lang="en">Almond PR. [et al.]. AAPM's TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams. Medical Physics. 1999;26(9):1847-1870. DOI: 10.1118/1.598691</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Kry, S.F. TLD and OSLD dosimetry systems for remote audits of radiotherapy external beam calibration / S.F. Kry, P. Alvarez, A. Molineu [et al.] // Radiation Measurements. – 2013. – Vol. 57. – P. 9–14. DOI: 10.1016/j.radmeas.2013.08.003</mixed-citation><mixed-citation xml:lang="en">Kry SF. [et al.]. TLD and OSLD dosimetry systems for remote audits of radiotherapy external beam calibration. Radiation Measurements. 2013;57:9-14. DOI: 10.1016/j.radmeas.2013.08.003</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Poppe, B. Two-dimensional ionization chamber arrays for IMRT plan verification / B. Poppe, A. Blechschmidt, A. Djouguela [et al.] // Medical Physics. – 2006. – Vol. 33, № 4. – P. 1005–1015. DOI: 10.1118/1.2198328</mixed-citation><mixed-citation xml:lang="en">Poppe B. [et al.]. Two-dimensional ionization chamber arrays for IMRT plan verification. Medical Physics. 2006;33(4):1005-1015. DOI: 10.1118/1.2198328</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Niroomand-Rad, A. Radiochromic film dosimetry: recommendations of AAPM Radiation Therapy Committee Task Group 55 / A. Niroomand-Rad, C.R. Blackwell, B.M. Coursey [et al.] // Medical Physics. – 1998. – Vol. 25, № 11. – P. 2093–2115. DOI: 10.1118/1.598398</mixed-citation><mixed-citation xml:lang="en">Niroomand-Rad A. [et al.]. Radiochromic film dosimetry: recommendations of AAPM Radiation Therapy Committee Task Group 55. Medical Physics. 1998;25(11):2093-2115. DOI: 10.1118/1.598398</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
